Chronic Inflammation. From Basic Research to Therapy
Course content
The students will obtain knowledge, skills and competences within the immunological mechanisms underlying development of autoimmunity and chronic inflammation. The couse contains elements of immunology and signalling mechanisms, disease pathogenesis, symptoms, diagnostics and therapy as well as the use of cellular and animal models, biomarkers and novel drugs in particular for major chronic inflammatory diseases, e.g. psoriasis and inflammatory bowel disease. It is the aim that the student will achieve a conceptual understanding which makes him/her able to contribute directly to research projects in the field as well as to have a professional dialogue with fellow researchers and clinicians within the field.
MSc Programme in Biochemistry - restricted elective
To attain course attestation, the student shall have obtained the following learning outcomes :
Knowledge: (the student will be able to)
- Explain the immunological mechanisms, innate and adaptive, which give rise to development of autoimmunity and chronic inflammation
- Explain the mechanims of signal transduction by major classes of innate and adaptive immune receptors
- Explain the interaction between immune mechanisms, genetics and environmental factors for selected autoimmune/chronic inflammatory disorders
- Explain and discuss the relevance of standard animal models within the field
- Explain the epidemiology, symptoms, diagnostics and treatment for selected autoimmune/chronic inflammatory disorders
- Explain the mechanisms of action for various anti-inflammatory drugs
- Explain and discuss basic research and drug development within the field
Skills: (the student will be able to)
- Suggest and perform a relevant immunological in-vitro or in-vivo model within inflammation research.
- Suggest novel approaches for increasing disease understanding
- Suggest biomarker analysis related to clinical research in inflammation. Interpret biomarker analysis in basic research and clinical trials within inflammation
- Suggest new strategies for drug development and implementation within an inflammatory disorder
Competences: (the student will obtain these general competences)
- Will be able to analyse and discuss experimentel results analysis used by researchers in the field of inflammation.
- Will improve their ability to read, analyse and present original research articles within the field of inflammation
- Will be able to suggest and initiate relevant research tools for projects within inflammation.
- Can contribute to interdisciplinary projects involving basic research, clinical research, biomarker and drug development within inflammation
Teaching and study methods: Lectures, classes, problems based
learning, journal club, student presentations of exercises.
Oral presentation of one or more exercises in the
class
Cellular and Molecular Immunology. Abul K. Abbas, Andrew H. Lichtman and Shiv Pillai. Elsevier. 10th Edition.
Peer-reviewed research articles on specific topics will be provided and should be read.
Previous participation in a basic immunology course is highly recommended
The course is primarily intended for students in Molecular Biomedicine, Biochemistry and Biology
Open for credit transfer students apply here
- ECTS
- 7,5 ECTS
- Type of assessment
-
On-site written exam, 2 hours under invigilation
- Examination prerequisites
-
Participation in journal clubs, problem-based learning excercises, and student presentations
- Aid
- No aids allowed
- Marking scale
- 7-point grading scale
- Censorship form
- No external censorship
Internal examiners.
- Re-exam
-
If 10 or fewer students have registered for re-exam, the examination form will be oral examination.
Assessment details: 30 minutes examination
Preparation: None
Aids: None
Criteria for exam assessment
To achieve the maximum grade of 12, the student shall be able to:
- Explain the immunological mechanisms, innate and adaptive, which give rise to development of autoimmunity and chronic inflammation
- Explain the mechanims of signal transduction by major classes of innate and adaptive immune receptors
- Explain the interaction between immune mechanisms, genetics and environmental factors for selected autoimmune/chronic inflammatory disorders
- Explain and discuss the relevance of standard animal models within the field
- Explain the epidemiology, symptoms, and treatment for selected autoimmune/chronic inflammatory disorders
- Explain the mechanisms of action for various anti-inflammatory drugs
- Explain and discuss basic research and drug development within the field
- Suggest relevant immunological in-vitro or in-vivo models for a given inflammatory/autoimmune disorder
- Suggest and/or analyse biomarker results related to basic and clinical research in inflammation. Interpret biomarker analysis in basic research and clinical trials within inflammation
- Suggest new strategies for drug development within an inflammatory disorder
- Analyse and discuss experimentel results and analyses used by researchers in the field of inflammation.
- Category
- Hours
- Lectures
- 26
- Preparation
- 162
- Theory exercises
- 16
- Exam
- 2
- English
- 206
Kursusinformation
- Language
- English
- Course number
- SMOK14003U
- ECTS
- 7,5 ECTS
- Programme level
- Full Degree Master
- Duration
-
1 block
- Placement
- Block 3
- Schedulegroup
-
A1
- Capacity
- 24 participants
- Studyboard
- Study Board for the Biological Area
Contracting department
- Department of Immunology and Microbiology
Contracting faculty
- Faculty of Health and Medical Sciences
Course Coordinator
- Mads Gyrd-Hansen (5-716b7d76684477797268326f7932686f)
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