Advanced Pharmaceutics
Course content
The course gives an overview on fundamental principles in advanced pharmaceutics. Advanced pharmaceutics topics, which will be addressed in the course, encompass (i) release mechanisms, (ii) pharmaceutical nanotechnology, (iii) biopharmacy, and (iv) manufacturing and quality control of advanced dosage forms. The first theme covers release mechanisms. This includes immediate release, controlled release, and targeted and triggered release of drugs. Pharmaceutical nanotechnology (theme ii) is addressing drug-polymer conjugates, delivery of biopharmaceuticals (peptides, proteins and nucleic acids), advanced drug delivery systems and delivery of vaccines. The third theme of the course (biopharmacy) will focus on evaluation of oral dosage forms, alternative administration routes for delivery of peptides and proteins, and aspects related to the drug development process in general (decision trees in drug development, PKPD modelling, regulatory requirements, the Biopharmaceutics Risk Assessment Road Map, personalized drug delivery, precision medicine and patient centric therapy). The course will also discuss manufacturing and quality control (theme iv). This includes manufacturing and analytical aspects of advanced dosage forms, continuous manufacturing, and quality control aspects of advanced dosage forms.
The overall aim of the course is to prepare the students to be able to select an advanced dosage form for a given drug, based on knowledge about the physicochemical properties of the drug, the advanced dosage form and the administration route. In addition, the student should be able to select methods for manufacturing, evaluation and quality control of advanced dosage forms.
MSc Programme in Pharmacy and Pharmaceutical Sciences - compulsory
MSc Programme in Medicinal Chemistry - elective
MSc Programme in Pharmaceutical Sciences (english programme) - restricted elective
At the end of this course, students are expected to be able to:
Knowledge
- Explain, define and summarize current advanced pharmaceutics principles
- Know and have an overview of current advanced pharmaceutics
Skills
- Able to critically identify, discuss and generalize the knowledge gained in advanced pharmaceutics
- Master the scientific methodologies in the field of advanced pharmaceutics
- Retrieve, assess and debate information on advanced dosage forms
- Communicate complex theoretical knowledge and experimental data
Competences
- Take responsibility and develop lifelong learning skills on advanced dosage forms
- Fundamentally understand the drug development process and the factors that have to be considered
The lectures are based on text books, selected review articles
and original scientific papers. The main teaching forms will be
lectures, 20 min videos and self-reflection, preparation for
lectures, class room teaching, supervised group work and student
presentations. The group work will be based on individual cases of
a selected topic of advanced pharmaceutics. Students will be
divided into groups of 4-6 students, and each group will be given
an assignment. The groups meet with the responsible lecturer twice
during the group work period to discuss the group work and to
prepare the groups for their presentations. In addition, the
students will be taught in “How to prepare a scientific
presentation (oral + poster)” via class room teaching. The group
work will be presented by the students ad either oral or poster
presentations, presented at two conference-style full-day workshops
at the end of the block (referred to as “Conference Day 1 and 2”).
Lectures (16 single lectures)
Classroom teaching (1 lecture)
Supervised groupwork on individual cases
Student presentations
Aulton´s Pharmaceutics (AP)
Pharmaceutics, Drug Delivery and Targeting (PDDT)
Selected review articles and original scientific papers
A Bachelor in Pharmacy.
None.
Open for credit transfer students and other external students. Apply here:
Credit transfer students:
Credit transfer student at SUND – University of Copenhagen
(ku.dk)
Other external students:
https://healthsciences.ku.dk/education/student-mobility/guest-students/
Credit transfer and other external students are welcomed on the course if there are seats available and they have the academic qualifications.
- ECTS
- 7,5 ECTS
- Type of assessment
-
Continuous assessment
- Type of assessment details
- The assessment consists of two parts. Both parts need to be
passed in order to pass the course:
1) Multiple choice test at the end of the course. Students have passed assessment part 1) when at least 80% of the questions are answered correctly.
2) Student assessment within the group work: Each student will be assessed according to the following criteria: A) Each student in a group has contributed equally to the group work. B) The group work has been submitted and presented at Conference Day 1 or 2. C) Each student has fully attended Conference Day 1 and 2. Each student has actively participated (either in presentation or as opponent) on Conference Day 1 or 2. Students have passed assessment part 2) only if ALL assessments criteria have been fulfilled.
How to improve an unacceptable course certificate:
Before the end of the re-exam period, failed students have an option to improve an unacceptable course certificate. Failed students need to write a comprehensive report on a subject determined by the course responsible, followed by an oral exam on the entire course content. - Aid
- All aids allowed
- Marking scale
- passed/not passed
- Censorship form
- No external censorship
Criteria for exam assessment
To achieve a course certificate the students must be able to:
Knowledge
- Explain, define and summarize current advanced pharmaceutics principles
- Know and have an overview of current advanced pharmaceutics
Skills
- Able to critically identify, discuss and generalize knowledge gained in advanced pharmaceutics
- Master the scientific methodologies in the field of advanced pharmaceutics
- Retrieve, assess and debate information on advanced dosage forms
- Communicate complex theoretical knowledge and experimental data
Competences
- Take responsibility and develop lifelong learning skills on advanced dosage forms
- Fundamentally understand the drug development process and the factors that have to be considered
Single subject courses (day)
- Category
- Hours
- Lectures
- 32
- Class Instruction
- 2
- E-Learning
- 56
- Project work
- 100
- Seminar
- 16
- English
- 206
Kursusinformation
- Language
- English
- Course number
- SFAK20001U
- ECTS
- 7,5 ECTS
- Programme level
- Full Degree Master
- Duration
-
1 block
- Placement
- Block 2
- Schedulegroup
-
AFurthermore, Friday (morning as well as afternoon) will be used in block week 8.
- Capacity
- 230 students
- Studyboard
- Study Board of Pharmaceutical Sciences
Contracting department
- Department of Pharmacy
Contracting faculty
- Faculty of Health and Medical Sciences
Course Coordinators
- Thomas Rades
(12-776b727064763175646768764376787167316e7831676e)
Hovedansvarlig - Camilla Foged (13-6765716d707065326a736b69684477797268326f7932686f)
Teacher
Thomas Rades
Camilla Foged
Jukka Rantanen
Anette Müllertz
Timetable
- 24E-B2-2;SFAK20001-H1;;Advanced Pharmaceutics
- 24E-B2-2;SFAK20001-H2;;Advanced Pharmaceutics
- 24E-B2-2;SFAK20001-H3;;Advanced Pharmaceutics
- 24E-B2-2;SFAK20001-H4;;Advanced Pharmaceutics
- 24E-B2-2;SFAK20001-H5;;Advanced Pharmaceutics
- 24E-B2-2;SFAK20001-H6;;Advanced Pharmaceutics
- 24E-B2-2;SFAK20001-H7;;Advanced Pharmaceutics
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