Heterocyclic Chemistry
Course content
- Synthesis and reactivity of simple heteroaromatic compounds: pyridines, quinolines, diazines, pyrylium salts, pyrones, furans, thiophenes, indoles and different five-membered rings with two heteroatoms.
- Nomenclature in heterocyclic chemistry.
- Some applications of heterocyclic compounds.
MSc Programme in Medicinal Chemistry
MSc Programme in Chemistry with a minor subject
Skills:
The student should be able to identify differences in reactivities
of heterocyclic compounds and be able to demonstrate how
heterocyclic compounds can be prepared from simple starting
materials. Moreover, the student should be able to name both
mono- and polycyclic heterocyclic compounds.
Knowledge:
Synthesis and reactivity of heterocyclic compounds. Particular
focus on pyridines, quinolines, diazines, pyrylium salts, pyrones,
furans, thiophenes, pyrrols, indoles, benzothiophenes, and
benzofurans.
Competences:
The student should be able to suggest syntheses of simple
heterocyclic compounds and explain the reactivity of heteroaromatic
compounds.
Lectures + Class room exercises
- J. A. Joule, K. Mills, ”Heterocyclic Chemistry”, 5th Ed., Blackwell Publishing
- M. B. Nielsen, Notes: Naming Heterocyclic Compounds
The student should be familiar with the general chemistry of the
carbonyl group, including nucleophilic addition, conjugate
addition, nucleophilic substitution at the carbonyl group, imine
formation, enolate formation, and specific enol equivalents. In
regard to carbonyl chemistry, the student should be familiar with
the aldol and Claisen ester condensations. In addition, knowledge
on the Diels-Alder cycloaddition is expected. Terms such as regio-,
chemo-, and stereoselectivity are prerequisites as well as
knowledge on common protecting groups for carbonyls, amines, and
alcohols.
Academic qualifications equivalent to a BSc degree is
recommended.
- ECTS
- 7,5 ECTS
- Type of assessment
-
Oral examination, 30 minutes (no preparation time)
- Aid
- Without aids
- Marking scale
- 7-point grading scale
- Censorship form
- No external censorship
Several internal examiners
- Re-exam
-
Same as the ordinary exam
Criteria for exam assessment
See Learning outcomes
Single subject courses (day)
- Category
- Hours
- Lectures
- 25
- Preparation
- 156,5
- Theory exercises
- 24
- Exam
- 0,5
- English
- 206,0
Kursusinformation
- Language
- English
- Course number
- NKEK22005U
- ECTS
- 7,5 ECTS
- Programme level
- Full Degree Master
- Duration
-
1 block
- Placement
- Block 3
- Schedulegroup
-
C
- Capacity
- No limitation – unless you register in the late-registration period (BSc and MSc) or as a credit or single subject student.
- Studyboard
- Study Board of Physics, Chemistry and Nanoscience
Contracting department
- Department of Chemistry
Contracting faculty
- Faculty of Science
Course Coordinator
- Mogens Brøndsted Nielsen (3-72677345686d6a7233707a336970)
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Kursusinformation for indskrevne studerende