Heterocyclic Chemistry

Course content

  • Synthesis and reactivity of simple heteroaromatic compounds: pyridines, quinolines, diazines, pyrylium salts, pyrones, furans, thiophenes, indoles and different five-membered rings with two heteroatoms.
  • Nomenclature in heterocyclic chemistry.
  • Some applications of heterocyclic compounds.
Education

MSc Programme in Medicinal Chemistry

MSc Programme in Chemistry with a minor subject

Learning outcome

Skills:
The student should be able to identify differences in reactivities of heterocyclic compounds and be able to demonstrate how heterocyclic compounds can be prepared from simple starting materials. Moreover, the student should be able to name both mono- and polycyclic heterocyclic compounds. 


Knowledge:
Synthesis and reactivity of heterocyclic compounds. Particular focus on pyridines, quinolines, diazines, pyrylium salts, pyrones, furans, thiophenes, pyrrols, indoles, benzothiophenes, and benzofurans.

 

Competences:
The student should be able to suggest syntheses of simple heterocyclic compounds and explain the reactivity of heteroaromatic compounds.

Lectures + Class room exercises

  • J. A. Joule, K. Mills, ”Heterocyclic Chemistry”, 5th Ed., Blackwell Publishing
  • M. B. Nielsen, Notes: Naming Heterocyclic Compounds

The student should be familiar with the general chemistry of the carbonyl group, including nucleophilic addition, conjugate addition, nucleophilic substitution at the carbonyl group, imine formation, enolate formation, and specific enol equivalents. In regard to carbonyl chemistry, the student should be familiar with the aldol and Claisen ester condensations. In addition, knowledge on the Diels-Alder cycloaddition is expected. Terms such as regio-, chemo-, and stereoselectivity are prerequisites as well as knowledge on common protecting groups for carbonyls, amines, and alcohols.

Academic qualifications equivalent to a BSc degree is recommended.

ECTS
7,5 ECTS
Type of assessment
Oral examination, 30 minutes (no preparation time)
Aid
Without aids
Marking scale
7-point grading scale
Censorship form
No external censorship
Several internal examiners
Re-exam

Same as the ordinary exam

Criteria for exam assessment

See Learning outcomes

Single subject courses (day)

  • Category
  • Hours
  • Lectures
  • 25
  • Preparation
  • 156,5
  • Theory exercises
  • 24
  • Exam
  • 0,5
  • English
  • 206,0

Kursusinformation

Language
English
Course number
NKEK22005U
ECTS
7,5 ECTS
Programme level
Full Degree Master
Duration

1 block

Placement
Block 3
Schedulegroup
C
Capacity
No limitation – unless you register in the late-registration period (BSc and MSc) or as a credit or single subject student.
Studyboard
Study Board of Physics, Chemistry and Nanoscience
Contracting department
  • Department of Chemistry
Contracting faculty
  • Faculty of Science
Course Coordinator
  • Mogens Brøndsted Nielsen   (3-7d727e507378757d3e7b853e747b)
Saved on the 18-04-2024

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