Theoretical Molecular Genetics

Course content

The molecular mechanisms underlying genetics, i.e. the segregation of the genetic information from parents to offspring, will be explored. This includes recombination, gene conversion, and cloning by positional mapping and by complementation. The causes of different types of mutations and the pathways of DNA repair. Genetic interactions like suppression and synthetic lethality. The topics also include gene regulation, chromatin structure and an introduction to epigenetics. The power of molecular genetics in model organisms to address biological question will also be demonstrated through the studies of research articles.


MSc Programme in Biochemistry
MSc Programme in Biology
MSc Programme in Biology with a minor subject
MSc Programme in Molecular Biomedicine

Learning outcome

The course offers a thorough understanding of genetic inheritance and genetic interactions, which is prerequisite for analysis of modern high though put sequencing data, and equips the student to participate in the ongoing revolution of basic biological research, medicine, and production,  that the rapid development of sequencing, gene editing and gene design is bringing about.


The participants in the course will acquire a solid background in the principles of genetics and get an introduction to the latest developments while integrating genetics and molecular biology.
The acquired knowledge will enable the student to apply powerful genetic tools for addressing biological questions.


The participants will develop quantitative, analytical skills with which to interpret experimental data and solve problems in classical and modern molecular genetics. The acquired knowledge will enable the student to apply powerful genetic tools for addressing biological questions. Presentation and discussion of data from peer reviewed articles in the fields of molecular biology and genetics.


  • The student will be able to solve problems in recombination, mutation, function and regulation of genes and DNA sequences, gene isolation plus gene and genome structure.
  • The student will be able to integrate material from various scientific topics and suggest mechanistic models.
  • The student will be able to present a scientific article and also act as a questioner/opponent for a scientific article in English.

Lectures and problem solving.
Introduction to articles.
Presentation of articles.

See Absalon.

The course is open to students at the Master level as well as students at the Bachelor level, and others with a relevant biological background including basic knowledge in genetics and molecular biology.

Academic qualifications equivalent to a BSc degree is recommended.

To obtain a full block understanding modern genetics, this course is fully integrated with the course Experimental Molecular Genetics.


Oral feedback after problem exercises.

7,5 ECTS
Type of assessment
Written examination, 4 hours under invigilation
Type of assessment details
All aids allowed
Marking scale
7-point grading scale
Censorship form
No external censorship
One internal examiner
Criteria for exam assessment

In order to obtain the grade 12 the student should convincingly and accurately demonstrate the knowledge, skills and competences described under Learning Outcome.


Single subject courses (day)

  • Category
  • Hours
  • Lectures
  • 12
  • Class Instruction
  • 18
  • Preparation
  • 136
  • Theory exercises
  • 36
  • Exam
  • 4
  • English
  • 206


Course number
7,5 ECTS
Programme level
Full Degree Master

1 block

Block 1
No limitation
The number of seats may be reduced in the late registration period
Study Board for the Biological Area
Contracting department
  • Department of Biology
Contracting faculty
  • Faculty of Science
Course Coordinator
  • Christian Holmberg   (5-686d74717245676e7433707a336970)
Saved on the 28-02-2023

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