Organic Chemistry

Course content

The Organic Chemistry course covers structure and mechanisms in organic chemistry with an emphasis on physical organic chemistry.

The major topics are:

 

-       Chemical bonding and structures (electronegativity, VSEPR, Lewis structures, hybridization, QMOT, orbital mixing);

-       Stereochemistry (configuration, conformation, chirality);

-       Conformationally, sterically and stereoelectronic effects (thermodynamic, kinetic);

-       Solutions and non-covalent binding forces (strong and weak interactions)

-       Acid-Base chemistry (definitions and implications of pH and pKa);

-       Energy surfaces and Kinetics (transition state theory, Hammond postulate, More O’Ferral-Jencks plots)

-       Isotope effects (theory and practice)

-       LFER (Hammett, Bronsted relationship, enthalpy-entropy compensation)

-       Catalysis (General and specific acid/base catalysis)

-       Nucleophilic substitution (at sp2, at sp3, types, leaving groups, anchimeric assistance, carbocations);

-       Addition/elimination/rearrangement/isomerization

-       Concerted pericyclic reactions (cycloadditions, sigmatropic rearangements, FMO theory, electrocyclization)

-       Radical reactions (reaction patterns, stability, substituent effects);

-       Introduction to organometallic chemistry (catalysis, reactions and structures).

 

And special topics related to the above topics.

 

The teaching will to a large extent follow the themes in the teaching book chapters, but additional literature will be used to support each topic. The additional literature will mainly be classic and contemporary articles and concepts in organic chemistry. When possible and appropriate, examples from the teachers own research will be used as examples of applied physical organic chemistry. Each topic will be introduces by the lecturer followed by discussions on the class. Exercises for each chapter will be handed out and discussed on the class based on the questions from the textbook or independently prepared quiz.

It is required that all students present at least one research paper during the course. 

Education

MSc Programme in Chemistry
MSc Programme in Chemistry with a minor subject

Learning outcome

After passing the course the student should be able to:

Knowledge:

Describe reactions using physical organic chemistry.

Justify selectivities between products on the basis of physical organic chemistry.

Skills:

Apply the theory to solve practical problems in organic chemistry and elucidate the mechanisms of the desired and undesired reactions.

Competencies:

Explain  and discuss the above topics. Analyze reactions on the basis of physical organic chemistry.

The teaching is divided into lectures by the teacher (and invited lecturers), student presentations of research papers and exercises (solved by the students at home – discussed on the class). Special topics and own experiences will be included when appropriate in the context

Course material will be indicated on Absalon

Basic competencies physical chemistry, quantum chemistry, inorganic chemistry are necessary and intermediate competencies in organic chemistry and organic synthesis  are necessary (equivalent to KemiOrg and (Vid)OrgSyn).

Academic qualifications equivalent to a BSc degree is recommended.

Written
Oral
Peer feedback (Students give each other feedback)
ECTS
15 ECTS
Type of assessment
Written examination, 4.00 h under invigilation
Oral examination, 20 min. (no preparation time)
Type of assessment details
Midterm Essay (10%)
Written examination, 4.00 h under invigilation (45%)
Oral examination, 20 min. (no preparation time) (45%)

The written and oral exams are weighted equally

Mid-term Essays:
The written exam consists of an essay. At the beginning of block 4 we will shortly discuss the essays and the students will receive feed-back. It is recommended to write the required essay as soon as possible after classroom teaching in the essay subjects has been covered.
The course has been selected for ITX exam.
See important information about ITX-exams at Study Information, menu point: Exams -> Exam types and rules -> Written on-site exams (ITX).
Aid
Only certain aids allowed

Only certain aids allowed

Midterm essay: open-book

Written examination: molecular building models are allowed

Oral examination: no aids allowed

Marking scale
7-point grading scale
Censorship form
No external censorship
several internal examiners
Criteria for exam assessment

Adequate and profound presentation and explanation of the topics in the written and oral examination will result in the grade 12. Basic understanding of the topics and the ability to explain them in context of presented problems is sufficient for passing the course.

Single subject courses (day)

  • Category
  • Hours
  • Lectures
  • 28
  • Preparation
  • 323
  • Theory exercises
  • 56
  • Exam
  • 5
  • English
  • 412

Kursusinformation

Language
English
Course number
NKEK13006U
ECTS
15 ECTS
Programme level
Full Degree Master
Duration

2 blocks

Placement
Block 3 And Block 4
Schedulegroup
B
Capacity
No admission restriction
The number of seats may be reduced in the late registration period
Studyboard
Study Board of Physics, Chemistry and Nanoscience
Contracting department
  • Department of Chemistry
Contracting faculty
  • Faculty of Science
Course Coordinator
  • Jiwoong Lee   (11-6e6d7b7373726b3270696944676c6971326f7932686f)
Teacher

Jiwoong Lee

Saved on the 27-10-2022

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