Clinical Translational Medicine

Course content

  • Translational research study design
  • How to develop and interpret PDX models
  • Automatized drug-screening in real time - for patient care
  • Clinical trial design
  • Communication training between patients, clinicians, basic scientist and industry
  • Phase 1 studies
  • First in human studies
  • Discussion clinical cases including ethical issues
  • Career moves from academia to industry
Education

BRIDGE - Translational Excellence Programme

 

Learning outcome

On completion of the course, the participants should be able to:

Knowledge

  • Relate how thorough characterization (molecular, immunological, imaging) of the individual patient or patient’s samples may be used for direct selection of patient treatment/care
  • Explain how information from biological experiments (in vitro and animal models) can be used as a platform for designing investigations in patients
  • Discuss how biological experiments may lead to drug development
  • Describe how to bring a preclinical drug to phase 1, basic requirements
  • Describe Phase 1 -> 3 trials
  • Plan a translational study with material from a clinical trial
  • Describe different studies, non-inferior vs. superiority studies

 

Skills

  • Integrate knowledge obtained from all other courses into translational clinical research
  • Critically evaluate preclinical data -  from a clinical point of view
  • Generate novel ideas for clinical trials from preclinical observations
  • Implement research results in clinical practice
  • Solve unmet clinical needs/questions by designing the clinically relevant preclinical/ biological experiments

 

Competences

  • Integrate  basic biology  into clinical knowledge
  • Assess ethical considerations of how to implement new molecular tools and conduct studies with patients
  • Understand the central aspects of clinical translational medicine and be able to discuss and communicate these to other scientists, clinicians, and the public

Individual projects – presentations
Cathedral lectures
Industry visit
Patient involvement – a story from a patient
Phase 1 visit

To be added

Participants must meet the admission criteria in BRIDGE - Translational Excellence Programme

Oral
Continuous feedback during the course of the semester
ECTS
0 ECTS
Type of assessment
Continuous assessment
Course participation
Attendance and active participation
Aid
All aids allowed
Marking scale
passed/not passed
Censorship form
No external censorship
Criteria for exam assessment

Knowledge

  • Relate how thorough characterization (molecular, immunological, imaging) of the individual patient or patient’s samples may be used for direct selection of patient treatment/care
  • Explain how information from biological experiments (in vitro and animal models) can be used as a platform for designing investigations in patients
  • Discuss how biological experiments may lead to drug development
  • Describe how to bring a preclinical drug to phase 1, basic requirements
  • Describe Phase 1 -> 3 trials
  • Plan a translational study with material from a clinical trial
  • Describe different studies, non-inferior vs. superiority studies

 

Skills

  • Integrate knowledge obtained from all other courses into translational clinical research
  • Critically evaluate preclinical data -  from a clinical point of view
  • Generate novel ideas for clinical trials from preclinical observations
  • Implement research results in clinical practice
  • Solve unmet clinical needs/questions by designing the clinically relevant preclinical/ biological experiments

 

Competences

  • Integrate  basic biology  into clinical knowledge
  • Assess ethical considerations of how to implement new molecular tools and conduct studies with patients
  • Understand the central aspects of clinical translational medicine and be able to discuss and communicate these to other scientists, clinicians, and the public

Part time Master and Diploma courses

  • Category
  • Hours
  • Course Preparation
  • 5
  • Excursions
  • 4
  • Lectures
  • 22
  • Practical Training
  • 6
  • Project work
  • 5
  • English
  • 42

Kursusinformation

Language
English
Course number
SBRI19015U
ECTS
0 ECTS
Programme level
Part Time Master
Ph.D.
Duration
Schedulegroup
See course dates and course programme in Absalon
Capacity
15 participants
Studyboard
Study Board for the Professionel Master´s Degree Programmes at The Faculty og Health and Medical Science
Contracting department
  • Department of Clinical Medicine
Contracting faculty
  • Faculty of Health and Medical Sciences
Course Coordinator
  • Kirsten Grønbæk   (17-6e6c7576776871316a757268716564686e4365756c66316e7831676e)
Saved on the 19-09-2019

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