Knowledge

• Understand mathematical/physics concepts (stability analysis, oscillation theory, synchronization theory, reaction-diffusion equations)

• Understand computational algorithms behind Matlab scripts related to biosimulations

• Explain morphology and dynamics of biological networks and their relevance to normal and pathological conditions

• Understand what assumptions and simplifications are needed to build a model

• Understand underlying signaling mechanisms and corresponding control parameters in a model related to a certain disease

Skills

• Analyze a scientific article on physiological modeling and related time-series analysis, critically assess the use of methods and published results

• Analyze complex networks of the human body by treating in sequence problems at the intracellular, intercellular, whole organ and systemic levels

• Perform theoretical and computational analysis of dynamical patterns in biological networks and reveal parameters responsible for pathological conditions

• Convey a physiological dynamical problem into a report and a power point presentation

Competence

• To formulate mechanism-based models and choose appropriate computational methods to investigate them

• To interpret dynamical features of the biomedical systems in term of biology and mathematics

• To integrate fundamental knowledge from physics, mathematics and biology to provide better understanding of regulatory mechanisms at different levels of organization