Advanced Bacteriology1

Course content

Theme 1: Social bacterial interactions

  • Bacterial interactions, Quorum sensing, Socio-microbiology


Theme 2:  Microbial biofilm and evolution

  • Biofilms, Evolution of bacteria


Theme 3: Bacterial mobile genetic elements

  • Plasmids, transposons, and bacteriophages
  • Horizontal transfer of plasmids in natural environments


Theme 4: Phenotypic heterogeneity

  • Phenotypic plasticity, Adaption to environmental change
  • Phenotypic heterogeneity in isogenic populations
Education

MSc Programme in Biology
MSc Programme in Biochemistry
MSc Programme in Molecular Biomedicine

MSc Programme in Biology with a minor subject

Learning outcome

By the end of the course students are expected to be able to master:

Knowledge:

  • describe the molecular mechanisms and evolutionary basis of social bacterial interactions and behaviour
  • describe the different mechanisms behind horizontal gene transfer among bacteria
  • describe the prokaryotic species concept and evaluate different species definitions


Skills:

  • evaluate the importance of biofilm formation to bacterial survival
  • evaluate quorum sensing in relation to biofilm formation and bacterial pathogenesis
  • evaluate the concept of sociomicrobiology and analyse the importance of bacterial interactions
  • evaluate the role of phenotypic heterogeneity in isogenic population as an adaption to environmental change
  • analyse the evolution and phylogeny of bacteria
  • analyse horizontal transfer of plasmids in natural environments


Competences:

  • use and evaluate classic and molecular experimental methods to research central topics covered in the course and subsequently analyse data
  • put into a plasmid pespective the evolution of antibiotic resistance, both in human infections and in various environments
  • analyse, put into perspective, and criticize the primary scientific literature
  • perform oral presentation of acquired knowledge and ideas

Generally include two weekly 2-hour discussion classes (Tuesdays from 9.00-11.00 and Thursdays from 9.00-11.00), two lectures (Tuesdays from 11.00-12.00 and Thursdays from 11.00-12.00), and a lecture in "New trends in microbiology" (Friday afternoon). Practical take place Thursdays (13.00-17.00)

See Absalon.

Introductory courses in molecular biology and microbiology are recommended.

Written
Oral
Continuous feedback during the course of the semester
Feedback by final exam (In addition to the grade)
ECTS
7,5 ECTS
Type of assessment
Oral examination, 20 minutes
Final oral exam based on curriculum, 20 minutes without preparation. All exam questions will be published 10 days before the exam.
Aid
Only certain aids allowed

Students may bring their own notes.

Marking scale
7-point grading scale
Censorship form
External censorship
Criteria for exam assessment

In order to obtain the grade 12 the student should convincingly and accurately demonstrate the knowledge, skills and competences described under Learning Outcome.

Single subject courses (day)

  • Category
  • Hours
  • Exam
  • 1
  • Preparation
  • 125
  • Lectures
  • 18
  • Seminar
  • 27
  • Practical exercises
  • 30
  • Project work
  • 5
  • English
  • 206