Kursussøgning, efter- og videreuddannelse – Københavns Universitet

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Kursussøgning, efter- og videreuddannelse

Supramolecular and Macromolecular Chemistry (KemiSM)

Practical information
Study year 2016/2017
Block 2
Programme level Bachelor
Course responsible
  • Mogens Brøndsted Nielsen (3-7d727e507378757d3e7b853e747b)
  • Department of Chemistry
Course number: NKEB13017U

Course content

Macrocyclic compounds, including host molecules for cations, anions, and neutral molecules.
Mechanically interlocked molecules (catenanes and rotaxanes).
Template-directed synthesis.
Self-organization and self-assembly.
Enzyme-substrate complexes and biomimetic catalysis.
Supramolecular polymers.
Non-covalent interactions.
Solvent effects.
Application of electrochemical and spectroscopic techniques.
Supramolecular devices.

Learning outcome



Qualifications:The student should be able to
- explain the criteria for the formation of supramolecular systems.
- judge the nature of noncovalent interactions which are responsible for the formation of a specific host-guest complex.
- estimate the size and distance dependence of intermolecular interactions.
- judge enthalpic and entropic contributions relevant for the formation of aggregates and host-guest complexes in solution.
- design supramolecular devices that explore light or electrochemical stimuli.
- design molecular sensors.
- judge and evaluate original publications that deal with design, synthesis and characterization of supramolecular systems and devices.

The student should be able to
- classify the weak noncovalent interactions.
- classify a variety of host molecules for specific guest molecules / ions.
- classify solvents based on macroscopic and molecular properties.
- demonstrate knowledge on experimental techniques typically used to characterize host-guest complexes in solution.
- identify templates for template-directed synthesis, for example for the synthesis of mechanically interlocked molecules.
- use electronic databases for finding original literature.

The student should gain knowledge on the noncovalent interactions responsible for the formation of supramolecular complexes and aggregates and how to design a host molecule for a specific guest molecule or ion. Moreover, knowledge on characterization techniques should be gained as well as on how to design supramolecular devices, sensors, and machines.



Recommended prerequisites

It is expected that the students are familiar with the content of the courses MatIntro, KemiO, KemiU1, KemiU2, KemiBin, AnvSpek and FysKem1.

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BSc Programme in Chemistry


Study Board of Physics, Chemistry and Nanoscience

Course type

Single subject courses (day)


Ole Hammerich


1 block


---- SKEMA LINK ----

Teaching and learning methods

Lectures + class room exercises + student presentations.


No limit


Partially in Danish


P.D. Beer, P.A. Gale, D.K. Smith, "Supramolecular Chemistry", Oxford University Press, 2003. 
Additional material (notes and articles) - available from Absalon. 
In particular, it is expected that the student him/herself finds relevant literature during the course. 


Category Hours
Lectures 21
Theory exercises 21
Exam 40
Preparation 124
English 206

Exam (Essay)

Type of assessment

Written assignment, 2 weeks
An essay has to be written based on either a theme or an article. The essay topic is decided by the teachers and announced 2 weeks before the essay is due.


All aids allowed

Marking scale

7-point grading scale

Criteria for exam assessment

According to the learning outcome

Censorship form

No external censorship
Several internal evaluators


The re-exam is an essay on a new topic chosen by the teachers (i.e., the re-exam is not a revised version of the failed essay). All students who have passed the mandatory group work (oral presentations) during the course are eligible for a re-exam. Students who do not meet the requirement should  follow the course again the next academic year

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