Kursussøgning, efter- og videreuddannelse – Københavns Universitet

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Kursussøgning, efter- og videreuddannelse

NMR Spectroscopy

Practical information
Study year 2016/2017
Block 2
Programme level Full Degree Master
Course responsible
  • Kaare Teilum (12-6d636374673076676b6e776f42646b71306d7730666d)
  • Department of Biology
  • Department of Biomedical Sciences
  • Department of Food Science
Course number: NBIK16001U

Course content

The aim of the course is for the student to learn basic density operator theory applied to nuclear magnetic resonance (NMR) spectroscopic experiments. This theoretical foundation will be used to analyze how various 1D and multidimensional NMR experiments can be applied for molecular identification and in the study of molecular structure and dynamics. Topics covered will include nuclear spin, chemical shift, scalar and dipolar couplings, relaxation, multi-dimensional spectroscopy, solid-state NMR and the NMR spectrometer. The concepts will be demonstrated by spectra of biological molecules such as proteins, carbohydrates and complex mixtures of metabolites.

Learning outcome

Having followed this course the student should have acquired the following:


  • About the basic properties of nuclear spin and density operator theory
  • About chemical shift,
  • About multidimensional NMR spectroscopy
  • About basic solid-state NMR
  • About the components of an NMR spectrometer
  • About signal acquisition and processing


  • Be able to process 1D and multidimensional experimental NMR data
  • Be able to analyze NMR spectra for assignment of chemical shifts
  • Be able to analyze the data from T1 and T2 relaxation experiments
  • Be able to calculate the effect of basic NMR pulse sequences
  • Be able to interpret basic NMR spectra in terms of molecular structure and dynamics
  • Be able to plan an NMR spectroscopic experiment


After the course the student will have competences in critically evaluating and discussing NMR spectroscopic experiments and the results of these. The student will have competences in presenting and discussing NMR spectroscopy in a precise and comprehensive scientific language.

Recommended prerequisites

This course will assume previous knowledge of very basic applied NMR spectroscopy corresponding to what is taught in organic chemistry.

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MSc Programme in Biochemistry
MSc Programme in Chemistry
MSc Programme in Nanoscience
MSc Programme in Physics


Study Board of Biomolecular Sciences and Technology

Course type

Single subject courses (day)


1 block


---- SKEMA LINK ----

Teaching and learning methods

Lectures, colloquia and lab excercises. NMR software.






See Absalon.


Category Hours
Lectures 14
Colloquia 28
Laboratory 4
Theory exercises 14
Preparation 142
Exam 4
English 206


Type of assessment

Written examination, 4 hours under invigilation


Without aids

Marking scale

7-point grading scale

Criteria for exam assessment

The grade 12 is given for an outstanding performance demonstrating complete fulfillment of the under "Learning outcome" described, with no or few minor weaknesses.

Censorship form

No external censorship
Several internal examiners


If less than 10 students are enrolled, the exam will be an oral examination in 25 minutes, with no preparation.

The 7 written assignments must be handed in no later than two weeks before the registration period for reexamination. All assignments must have been approved by the teacher before reexamination.

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