Kursussøgning, efter- og videreuddannelse – Københavns Universitet

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Kursussøgning, efter- og videreuddannelse

Experimental Higher Model Organisms

Practical information
Study year 2016/2017
Time
Block 3
Programme level Full Degree Master
ECTS 7,5 ECTS
Course responsible
  • John Mundy (5-767e776d82497c6c726e776c6e37747e376d74)
  • Department of Biology
Course number: NBIK13005U

Course content

Theoretical exercises, colloquia and lectures will give a critical review of the use of genetic model systems and strategies used in basic and applied research. Laboratory exercises will include a range of techniques such as

1) Vector construction and genome, transcriptome and/or proteome database mining

2) Genomic manipulations via homologous recombination, RNA interference and random insertional mutagenesis,

3) Stable transformation and transient transfection,

4) Transgenic analyses with marker enzymes and/or tagged proteins.

The techniques will be applied to cells and organisms such as vertebrate cell lines, the worm C. elegans, the fruit fly D. melanogaster, the moss P. patens and/or the flowering plant A. thaliana.

Learning outcome

By the end of the course, students are expected to have the following knowledge, skills and competences:

Knowledge of the research fields with model organisms included in the curriculum covered by assigned reading, lectures, seminar presentations and written reports.

Skills to:

  • Explain developments in the fields presented by the teachers
  • Describe in detail the methodologies used in these fields
  • Explain and exemplify the technologies used in these fields
  • Present assigned original research papers
  • Submit assigned written papers
  • Be able to give a detailed description of and evaluate the exercises presented during the course


Competences to:

  • Discuss and criticize research articles orally and in writing
  • Interpret different types of experimental data introduced in the course
  • Discuss interdisciplinary aspects of the research covered in the course
  • Propose experiments to test models and questions raised in research on model organisms.

Recommended prerequisites

General Molecular Biology/Almen molekylærbiologi or an equivalent course

Education

MSc programme in Biology
MSc Programme in Biochemistry

Studyboard

Study Board of Biology and Animal Science

Course type

Single subject courses (day)

Duration

1 block

Schedulegroup

C
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Teaching and learning methods

Introduction lessons in theoretical backgrounds and practical classes including summaries and discussions of reports.

Language

English

Literature

See Absalon

Workload

Category Hours
Preparation 85
Lectures 28
Colloquia 21
Theory exercises 21
Project work 51
English 206

Exam

Type of assessment

Continuous assessment
Active participation in all exercises, presentation of published, original research papers, written reports. The grade will be given based on an overall evaluation.

Marking scale

7-point grading scale

Criteria for exam assessment

See Learning outcome.

Censorship form

No external censorship
One internal examiner

Re-exam

Re-examination requires an individual, oral presentation by the student to course instructors of:

1- One of the research articles presented by students during the foregoing course
2- One of the bioinformatics problems assigned to students during the foregoing course
3- One of the prosed experiment reports assigned to students  during the foregoing course

The oral presentation is set 3 hours (no aids allowed). The preparation time is  set for a week (all aids allowed).

 

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