Experimental Higher Model Organisms

Course content

Theoretical exercises, colloquia and lectures will give a critical review of the use of genetic model systems and strategies used in basic and applied research. Laboratory exercises will include a range of techniques such as

1) Vector construction and genome, transcriptome and/or proteome database mining

2) Genomic manipulations via homologous recombination, RNA interference and random insertional mutagenesis,

3) Stable transformation and transient transfection,

4) Transgenic analyses with marker enzymes and/or tagged proteins.

The techniques will be applied to cells and organisms such as vertebrate cell lines, the worm C. elegans, the fruit fly D. melanogaster, the moss P. patens and/or the flowering plant A. thaliana.

Education

MSc programme in Biology
MSc Programme in Biochemistry

Learning outcome

By the end of the course, students are expected to have the following knowledge, skills and competences:

Knowledge of the research fields with model organisms included in the curriculum covered by assigned reading, lectures, seminar presentations and written reports.

Skills to:

  • Explain developments in the fields presented by the teachers
  • Describe in detail the methodologies used in these fields
  • Explain and exemplify the technologies used in these fields
  • Present assigned original research papers
  • Submit assigned written papers
  • Be able to give a detailed description of and evaluate the exercises presented during the course


Competences to:

  • Discuss and criticize research articles orally and in writing
  • Interpret different types of experimental data introduced in the course
  • Discuss interdisciplinary aspects of the research covered in the course
  • Propose experiments to test models and questions raised in research on model organisms.

Introduction lessons in theoretical backgrounds and practical classes including summaries and discussions of reports.

See Absalon

General Molecular Biology/Almen molekylærbiologi or an equivalent course

ECTS
7,5 ECTS
Type of assessment
Continuous assessment
Active participation in all exercises, presentation of published, original research papers, written reports. The grade will be given based on an overall evaluation.
Marking scale
7-point grading scale
Censorship form
No external censorship
One internal examiner
Criteria for exam assessment

See Learning outcome.

Single subject courses (day)

  • Category
  • Hours
  • Preparation
  • 85
  • Lectures
  • 28
  • Colloquia
  • 21
  • Theory exercises
  • 21
  • Project work
  • 51
  • English
  • 206